Source: Cornell Chronicle
A study on horses has revealed that 42% of miscarriages and spontaneous abortions in the first two months of pregnancy are due to triploidy, a condition involving an extra set of chromosomes. This finding is significant as it aligns with similar chromosomal error patterns in human pregnancies. The research, led by Mandi de Mestre at Cornell University, analyzed 256 samples over 10 years, showing that chromosomal errors cause 57.9% of early pregnancy losses in horses.
These errors, particularly aneuploidy, are prevalent in the first 10 weeks of gestation, while partial chromosome deletions or duplications occur after 110 days. Horses serve as a valuable model for human pregnancy studies due to their similar gestation period and chromosomal structure. The findings will enhance clinical management and diagnostic testing for chromosomal abnormalities in equine pregnancies and provide insights into early human pregnancy loss. The study was published in the Proceedings of the National Academy of Sciences.
Read the full story HERE: https://news.cornell.edu/stories/2024/08/horse-miscarriages-offer-clues-causes-early-human-pregnancy-loss