Source: AAHA
Researchers at Texas A&M’s Gastrointestinal Laboratory have identified biomarkers that may predict gastrointestinal (GI) disease in dogs before symptoms appear. Focusing on Soft Coated Wheaten Terriers—prone to protein-losing enteropathy (PLE)—the study found that seemingly healthy dogs shared biomarker patterns with those already diagnosed, suggesting a “silent” phase of disease. The team used blood tests, gut microbiome analysis, and video endoscopy to collect data.
Led by Dr. Katie Tolbert, the goal is to prevent or lessen GI disease through early detection and dietary intervention. A follow-up study will test whether hydrolyzed or novel-protein diets can reduce or delay symptoms. Collaborating with Dr. Sara Jablonski of Michigan State University, who advocates diet-first treatment over aggressive immunosuppression, the researchers aim to change the clinical approach to PLE. Their work already shows promise, with many dogs achieving long-term stability through diet changes alone. The ultimate goal is breed-specific, preventative nutrition for longer, healthier canine lives.