Source: Yale News

In sunny Florida, an 11-year-old golden retriever named Hunter, despite having only three legs due to osteosarcoma, thrives with boundless energy. Once a search-and-rescue dog, Hunter now aids in training others. His cancer treatment, including amputation and chemotherapy, also involves a novel cancer vaccine developed by Yale’s Mark Mamula. This immunotherapy, currently under USDA review, has shown promising results in clinical trials, significantly extending survival rates for dogs with various cancers. Mamula’s inspiration stemmed from his research on autoimmune diseases, leading to a targeted immune response against tumors.

Collaborating with Veterinary oncologists, Mamula adapted the vaccine for dogs, recognizing the similarities between human and canine cancers. Over 300 dogs have received the vaccine, with notable success, leading to Mamula’s company aiming for wider distribution. The vaccine offers hope in advancing canine cancer treatment, marking a significant milestone in Veterinary oncology and bringing joy to countless dog owners like Hunter’s owner, Deana Hudgins.

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