Source: Phys Org

A new study published in Microbiology Spectrum shows that antimicrobial peptides (AMPs) can effectively combat Salmonella infections in chickens, offering a promising alternative to antibiotics. Led by Dr. Gireesh Rajashekara of the University of Illinois Urbana-Champaign’s College of Veterinary Medicine, the research identified short amino acid chains capable of killing multiple Salmonella strains both in laboratory tests and live chickens.
These peptides damage bacterial membranes and remain effective after exposure to heat and enzymes, making them suitable for poultry industry use. Because Salmonella from poultry products is a leading cause of U.S. foodborne illness, AMPs could significantly enhance food safety and public health while reducing antibiotic resistance. The team discovered two potent AMPs that reduced Salmonella loads in birds and plans to conduct large-scale trials, refine delivery through feed or water, and further investigate their mechanisms and potential against other pathogens such as E. coli.