Source: The Horse

Researchers are exploring natural and high-tech alternatives to antibiotics in horses to combat rising antimicrobial resistance and protect global health. While antibiotics remain lifesaving, their overuse can disrupt the microbiome and drive resistant bacteria. Because wounds are easily accessible, many alternatives target local infections. Studies show that medical-grade honey, garlic, ginger, and certain medicinal plants have strong antibacterial properties, while topical antiseptics, hydrogen peroxide, platelet-based therapies, and vitamin B2 activated with ultraviolet light also show promise. 
For internal infections, scientists are developing probiotics, antivirulence drugs, bacteriophages, and advanced delivery systems, particularly to fight Rhodococcus equi in foals. Immune-supporting strategies, including fermented brewer’s yeast and vaccines, may further reduce infection risk. Experts stress that these innovations support the One Health concept, linking animal, human, and environmental well-being. The goal is not to eliminate antibiotics, but to reduce routine use and preserve their effectiveness through targeted, evidence-based alternatives.