Source: EurekAlert
A study published in ImmunoHorizons highlights how analyzing immune system markers in dogs could transform Veterinary care through personalized diagnostics and treatments. Led by Dr. Ravi Sachidanandam with the Waltham Research Institute, researchers examined T cell receptors (TCRs)—key components of adaptive immunity—in four breeds: Beagles, Labrador Retrievers, Norfolk Terriers, and Petit Basset Griffon Vendeens. They discovered that TCR repertoires are both individual-specific and breed-specific, suggesting that simple blood tests could track a dog’s immune profile over time and tailor care to genetic background.
The study also revealed that TCR diversity decreases with age, raising the possibility of creating “molecular clocks” to assess immunological age and predict susceptibility to infections or poor vaccine responses. This approach could enable early disease detection, better treatment strategies, and improved long-term outcomes. Future research aims to expand to more breeds and link TCR changes to specific health conditions, advancing preventive and personalized Veterinary medicine.
Read the full story HERE: https://www.eurekalert.org/news-releases/1095957