Source: AAHA
The Dog Aging Project aims to extend and improve the lives of dogs by studying genetic and lifestyle factors that impact aging. A key area of research is the Test of Rapamycin in Aging Dogs (TRIAD) clinical trial, which examines whether low doses of rapamycin, a drug used in human medicine, can extend canine lifespan and improve healthspan—the period of life free from chronic disease. Initial studies in mice suggest rapamycin preserves cardiac, muscle, and cognitive function.
Beyond medication, the project also explores how diet and exercise affect aging. Findings suggest that dogs fed once daily may have better health outcomes, and those with higher physical activity levels exhibit lower cognitive decline. The study also highlights the connection between dog and owner health, showing that shared habits influence both species’ longevity. Veterinarians and dog owners are encouraged to participate in the project, which seeks to benefit both dogs and their human companions.